Sublobar resection in high-risk patients for lobectomy: current and future strategy

Surgical resection by lobectomy is the gold standard of therapy for early stage non-small cell lung cancer. However, not all patients are medically fit to undergo surgery. In considered high-risk lobectomy, alternative strategies have been developed including radiofrequency ablation, cryoablation, microwave stereotactic radiation therapy, wedge resection, and segmentectomy. This work reviews definition high-risk, outcomes that associated with each treatment technique. Some technical points regarding versus segmentectomy noted. Future directions discussed in context at lobectomy.